Ambient fine particulate matter induces inflammatory responses of vascular endothelial cells through activating TLR-mediated pathway

Y Le, X Hu, J Zhu, C Wang… - … and Industrial Health, 2019 - journals.sagepub.com
role of Toll-like receptors (TLRs) on fine particulate matter (PM 2.5 )-induced inflammatory
responses … We found that the mRNA levels of TLR2, TLR4, and MyD88 in the mouse aortas of …

[HTML][HTML] … particulate matter induces airway inflammation by disturbing the balance between Th1/Th2 and regulation of GATA3 and Runx3 expression in BALB/c mice

L Pang, P Yu, X Liu, Y Fan… - Molecular medicine …, 2021 - spandidos-publications.com
inflammation response, especially in the asthmatic mouse … imbalance in Th1/Th2, has been
reported to be involved in … )2/TLR4/myeloid differentiation primary response protein M2yD88 …

Fine particulate matter (PM2. 5) aggravates apoptosis of cigarette-inflamed bronchial epithelium in vivo and vitro

T Zhou, Y Hu, Y Wang, C Sun, Y Zhong, J Liao… - Environmental …, 2019 - Elsevier
… between CS mice and control mice nor between CS mice and PM 2.5 -CS … inflammatory
response involved in PM 2.5 -induced lung injury is very similar to the inflammation involved in …

Sargassum horneri (Turner) inhibit urban particulate matter-induced inflammation in MH-S lung macrophages via blocking TLRs mediated NF-κB and MAPK activation

KKA Sanjeewa, TU Jayawardena, SY Kim… - Journal of …, 2020 - Elsevier
… ) play critical role during the inflammatory responses. The … Except for TLR2 and TLR4, the
present study firstly proved … of urban particulate matter on inflammatory responses of lung …

Carbon monoxide releasing molecule-2 protects against particulate matter-induced lung inflammation by inhibiting TLR2 and 4/ROS/NLRP3 inflammasome activation

CW Lee, MC Chi, LF Hsu, CM Yang, TH Hsu… - Molecular …, 2019 - Elsevier
mice was reduced by CORM-2. The results of this study suggested a protective role of CORM-2
in PM-induced lung inflammationinduce inflammatory responses via TLR2 and TLR4 by …

[HTML][HTML] MiR-140-5p/TLR4/NF-κB signaling pathway: crucial role in inflammatory response in 16HBE cells induced by dust fall PM2. 5

X Chen, T Deng, T Huo, F Dong, J Deng - … and Environmental Safety, 2021 - Elsevier
… lysis, disordered arrangement, and visible particulate matters adsorbed on the cells (as shown
by … signaling via the toll-like receptor 4-M D-2 complex on mouse peritoneal macrophages …

IL-33/ST2 signaling modulates Afghanistan particulate matter induced airway hyperresponsiveness in mice

R Berman, KW Kopf, E Min, J Huang… - Toxicology and Applied …, 2020 - Elsevier
… APM induced neutrophilic inflammation in mice was … signaling pathway is involved in the
inflammatory response to APM… regulation of TLR2 by internalized sST2 may play a role in RGS2 …

Inhibitory functions of maslinic acid on particulate matter-induced lung injury through TLR4-mTOR-autophagy pathways

SY Jeong, J Kim, EK Park, MC Baek, JS Bae - Environmental research, 2020 - Elsevier
… present study, we used a mouse model exposed to diesel PM … diesel PM 2.5 -induced
pulmonary inflammatory responses. … role in LPS-induced inflammation, though it may be involved

[HTML][HTML] Mechanistic implications of biomass-derived particulate matter for immunity and immune disorders

A Nagappan, SB Park, SJ Lee, Y Moon - Toxics, 2021 - mdpi.com
… reported that PM induces an imbalance of Th1/Th2 via TLR-… groups failed to induce important
inflammatory responses. Another … mice exposed to fine dust and RSV infected mice without …

A traditional herbal formula, Deng-Shi-Qing-Mai-Tang, regulates TLR4/NF-κB signaling pathway to reduce inflammatory response in PM2. 5-induced lung injury

Y Zhou, J Liu, C Jiang, J Chen, X Feng, W Chen… - Phytomedicine, 2021 - Elsevier
… Studies revealed that particulate matter 2.5 (PM2.5) enters … , TLR4/NF-κB signaling pathways
are reported to play a role … in rats with PM2.5-induced lung injury and inflammation to test …